TMC1 and TMC2 are cholesterol-dependent scramblases that regulate membrane homeostasis in auditory hair cells.
TMC1 and TMC2 are cholesterol-dependent scramblases that regulate membrane homeostasis in auditory hair cells. bioRxiv. 2025 Jul 04.
PMID: 40631239
Groove architecture controls lipid scrambling in simulations of protein and model systems.
Groove architecture controls lipid scrambling in simulations of protein and model systems. bioRxiv. 2025 Jul 01.
PMID: 40631228
Structural and functional basis of mechanosensitive TMEM63 channelopathies.
Structural and functional basis of mechanosensitive TMEM63 channelopathies. Neuron. 2025 Aug 06; 113(15):2474-2489.e5.
PMID: 40480214
In silico analyses of molecular force sensors for mechanical characterization of biological systems.
In silico analyses of molecular force sensors for mechanical characterization of biological systems. Biophys J. 2025 Mar 04; 124(5):829-843.
PMID: 39905731
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels.
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels. Elife. 2025 Jan 08; 12.
PMID: 39773557
Transmembrane channel-like 4 and 5 proteins at microvillar tips are potential ion channels and lipid scramblases.
Transmembrane channel-like 4 and 5 proteins at microvillar tips are potential ion channels and lipid scramblases. bioRxiv. 2024 Aug 23.
PMID: 39229161
In-Silico Analyses of Molecular Force Sensors for Mechanical Characterization of Biological Systems.
In-Silico Analyses of Molecular Force Sensors for Mechanical Characterization of Biological Systems. bioRxiv. 2024 Jul 22.
PMID: 39091752
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels.
Complexes of vertebrate TMC1/2 and CIB2/3 proteins form hair-cell mechanotransduction cation channels. bioRxiv. 2024 Jul 05.
PMID: 37398045
Elasticity and Thermal Stability are Key Determinants of Hearing Rescue by Mini-Protocadherin-15 Proteins.
Elasticity and Thermal Stability are Key Determinants of Hearing Rescue by Mini-Protocadherin-15 Proteins. bioRxiv. 2024 Jun 17.
PMID: 38948700
CELSR1, a core planar cell polarity protein, features a weakly adhesive and flexible cadherin ectodomain.
CELSR1, a core planar cell polarity protein, features a weakly adhesive and flexible cadherin ectodomain. Structure. 2024 04 04; 32(4):476-491.e5.
PMID: 38307021